Proinflammatory Cytokines and Bile Acids Upregulate ΔNp73 Protein, an Inhibitor of p53 and p73 Tumor Suppressors

Gastroesophageal reflux disease (GERD) is the main etiological factor behind the recent rapid increase in the incidence of esophageal adenocarcinoma. During reflux, esophageal cells are exposed to bile at low pH resulting in cellular damage and inflammation, which are known to facilitate cancer deve...

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Главные авторы: Zaika, Elena, Bhardwaj, Vikas, Wei, Jinxiong, Washington, Mary Kay, Souza, Rhonda, El-Rifai, Wael, Zaika, Alexander
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2013
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661465/
https://ncbi.nlm.nih.gov/pubmed/23717592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064306
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