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CYP2E1-dependent elevation of serum cholesterol, triglycerides, and hepatic bile acids by isoniazid
Isoniazid is the first-line medication in the prevention and treatment of tuberculosis. Isoniazid is known to have a biphasic effect on the inhibition–induction of CYP2E1 and is also considered to be involved in isoniazid-induced hepatotoxicity. However, the full extent and mechanism of involvement...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3661416/ https://ncbi.nlm.nih.gov/pubmed/23142471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2012.10.024 |
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