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CYP2E1-dependent elevation of serum cholesterol, triglycerides, and hepatic bile acids by isoniazid

Isoniazid is the first-line medication in the prevention and treatment of tuberculosis. Isoniazid is known to have a biphasic effect on the inhibition–induction of CYP2E1 and is also considered to be involved in isoniazid-induced hepatotoxicity. However, the full extent and mechanism of involvement...

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Detaylı Bibliyografya
Asıl Yazarlar: Cheng, Jie, Krausz, Kristopher W., Li, Feng, Ma, Xiaochao, Gonzalez, Frank J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661416/
https://ncbi.nlm.nih.gov/pubmed/23142471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2012.10.024
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