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Detecting negative selection on recurrent mutations using gene genealogy

BACKGROUND: Whether or not a mutant allele in a population is under selection is an important issue in population genetics, and various neutrality tests have been invented so far to detect selection. However, detection of negative selection has been notoriously difficult, partly because negatively s...

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Detalhes bibliográficos
Main Authors: Ezawa, Kiyoshi, Landan, Giddy, Graur, Dan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661350/
https://ncbi.nlm.nih.gov/pubmed/23651527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-14-37
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