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Detecting negative selection on recurrent mutations using gene genealogy

BACKGROUND: Whether or not a mutant allele in a population is under selection is an important issue in population genetics, and various neutrality tests have been invented so far to detect selection. However, detection of negative selection has been notoriously difficult, partly because negatively s...

詳細記述

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書誌詳細
主要な著者: Ezawa, Kiyoshi, Landan, Giddy, Graur, Dan
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661350/
https://ncbi.nlm.nih.gov/pubmed/23651527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-14-37
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