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Attenuation of autonomic reflexes by A803467 may not be solely caused by blockade of NaV 1.8 channels
In decerebrated rats, we determined the dose of A803467, a NaV 1.8 antagonist, needed to attenuate the reflex pressor responses to femoral arterial injections of lactic acid (24mM; ~0.1mL) and capsaicin (0.1μg), agents which stimulate thin fiber afferents having NaV 1.8 channels. We also determined...
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| Hoofdauteurs: | , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2013
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3661189/ https://ncbi.nlm.nih.gov/pubmed/23523647 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2013.03.015 |
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