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Indoleamine 2,3-dioxygenase activity and clinical outcome following induction chemotherapy and concurrent chemoradiation in Stage III non-small cell lung cancer

Indoleamine 2,3-dioxygenase (IDO) has recently been proposed to account for tumor-induced immunosuppression by influencing the conversion of tryptophan (Trp) into kynurenine (Kyn). The objective of our study was to correlate IDO activity with disease outcome in non-small cell lung cancer (NSCLC) pat...

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Detalhes bibliográficos
Main Authors: Creelan, Ben C., Antonia, Scott, Bepler, Gerold, Garrett, Timothy J., Simon, George R., Soliman, Hatem H.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661168/
https://ncbi.nlm.nih.gov/pubmed/23802083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.23428
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