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Human Vδ2 versus non-Vδ2 γδ T cells in antitumor immunity

The Vδ2 and non-Vδ2 (mainly Vδ1) subsets of human γδ T cells have distinct homing patterns and recognize different types of ligands, yet both exert potent antitumor effects. While the T-cell receptor of Vδ2 T cells primarily recognizes tumor cell-derived pyrophosphates, non-Vδ2 γδ T cells preferenti...

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Autors principals: Kabelitz, Dieter, Kalyan, Shirin, Oberg, Hans-Heinrich, Wesch, Daniela
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661159/
https://ncbi.nlm.nih.gov/pubmed/23802074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.23304
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