Recruitment of myeloid cells to the tumor microenvironment supports liver metastasis

Tumor-infiltrating immune cells play important roles in metastasis. We have recently revealed the recruitment of a specific myeloid cell subset (CD11b/Gr1(mid)) to hepatic metastases. Such a recruitment relies on CCL2/CCR2 signaling and acts to sustain metastatic growth. A similar cell subset was id...

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Auteurs principaux: Lim, Su Yin, Gordon-Weeks, Alex N., Zhao, Lei, Tapmeier, Thomas T., Im, Jae Hong, Cao, Yunhong, Beech, John, Allen, Danny, Smart, Sean, Muschel, Ruth J.
Format: Artigo
Langue:Inglês
Publié: Landes Bioscience 2013
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661156/
https://ncbi.nlm.nih.gov/pubmed/23802071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.23187
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