NPV-LDE-225 (Erismodegib) inhibits epithelial mesenchymal transition and self-renewal of glioblastoma initiating cells by regulating miR-21, miR-128, and miR-200

BACKGROUND: Glioblastoma multiforme is the most common form of primary brain tumor, often characterized by poor survival. Glioblastoma initiating cells (GICs) regulate self-renewal, differentiation, and tumor initiation properties and are involved in tumor growth, recurrence, and resistance to conve...

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Dettagli Bibliografici
Autori principali: Fu, Junsheng, Rodova, Mariana, Nanta, Rajesh, Meeker, Daniel, Van Veldhuizen, Peter J., Srivastava, Rakesh K., Shankar, Sharmila
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2013
Soggetti:
Basic and Translational Investigations
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661095/
https://ncbi.nlm.nih.gov/pubmed/23482671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/not011
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