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HER2 Expression Beyond Breast Cancer: Therapeutic Implications for Gynecologic Malignancies

HER2 or ErbB2 is a member of the epidermal growth factor family and is overexpressed in subsets of breast, ovarian, gastric, colorectal, pancreatic and endometrial cancers. HER2 regulates signaling through several pathways (Ras/Raf/mitogen-activated protein kinase and phosphatidylinositol-3 kinase/p...

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Détails bibliographiques
Auteurs principaux: English, Diana P., Roque, Dana M., Santin, Alessandro D.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3660991/
https://ncbi.nlm.nih.gov/pubmed/23529353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40291-013-0024-9
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