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Beyond trastuzumab: novel therapeutic strategies in HER2-positive metastatic breast cancer

The use of trastuzumab, a monoclonal antibody that targets the human epidermal growth factor receptor 2 (HER2) alteration present in 25 to 30% of breast cancers, has been associated with improved survival outcomes in both the adjuvant and metastatic settings. However, despite the robust clinical eff...

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Detalhes bibliográficos
Main Authors: Tsang, R Y, Finn, R S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251862/
https://ncbi.nlm.nih.gov/pubmed/22215104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2011.516
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