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Crystallization and preliminary X-ray diffraction analysis of the Cmr2–Cmr3 subcomplex in the CRISPR–Cas RNA-silencing effector complex

Clustered, regularly interspaced, short palindromic repeat (CRISPR) loci, found in prokaryotes, are transcribed to produce CRISPR RNAs (crRNAs). The Cmr proteins (Cmr1–6) and crRNA form a ribonucleoprotein complex that degrades target RNAs derived from invading genetic elements. Cmr2dHD, a Cmr2 vari...

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Detalhes bibliográficos
Main Authors: Osawa, Takuo, Inanaga, Hideko, Numata, Tomoyuki
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3660908/
https://ncbi.nlm.nih.gov/pubmed/23695584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309113011202
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