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Crystallization and preliminary X-ray diffraction analysis of an archaeal tRNA-modification enzyme, TiaS, complexed with tRNA(Ile2) and ATP

The cytidine at the first anticodon position of archaeal tRNA(Ile2), which decodes the isoleucine AUA codon, is modified to 2-agmatinylcytidine (agm(2)C) to guarantee the fidelity of protein biosynthesis. This post-transcriptional modification is catalyzed by tRNA(Ile)-agm(2)C synthetase (TiaS) usin...

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Detalhes bibliográficos
Main Authors: Osawa, Takuo, Inanaga, Hideko, Kimura, Satoshi, Terasaka, Naohiro, Suzuki, Tsutomu, Numata, Tomoyuki
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3212464/
https://ncbi.nlm.nih.gov/pubmed/22102245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309111034890
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