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Molecular mechanisms responsible for the differential effects of apoE3 and apoE4 on plasma lipoprotein cholesterol levels

OBJECTIVE: The goal of this study was to understand the molecular basis for how the amino acid substitution C112R that distinguishes human apolipoprotein (apo) E4 from apoE3 causes the more pro-atherogenic plasma lipoprotein cholesterol distribution that is known to be associated with expression of...

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書誌詳細
主要な著者: Li, Hui, Dhanasekaran, Padmaja, Alexander, Eric T., Rader, Daniel J., Phillips, Michael C., Lund-Katz, Sissel
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3660844/
https://ncbi.nlm.nih.gov/pubmed/23413428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.301193
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