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High-throughput Screening Identifies Aclacinomycin as a Radiosensitizer of EGFR-Mutant Non-Small Cell Lung Cancer

The endoplasmic reticulum (ER) provides a specialized environment for the folding and modification of trans-membrane proteins, including receptor tyrosine kinases (RTKs), which are vital for the growth and survival of malignancies. To identify compounds which disrupt the function of the ER and thus...

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Hlavní autoři: Bennett, Daniel C, Charest, Jonathan, Sebolt, Katrina, Lehrman, Mark, Rehemtulla, Alnawaz, Contessa, Joseph N
Médium: Artigo
Jazyk:Inglês
Vydáno: Neoplasia Press Inc. 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3660808/
https://ncbi.nlm.nih.gov/pubmed/23730419
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