Circulating Cell-Free DNA from Colorectal Cancer Patients May Reveal High KRAS or BRAF Mutation Load

We used a novel method based on allele-specific quantitative polymerase chain reaction (Intplex) for the analysis of circulating cell.free DNA (ccfDNA) to compare total ccfDNA and KRAS- or BRAF-mutated ccfDNA concentrations in blood samples from mice xenografted with the human SW620 colorectal cance...

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Hlavní autoři: Mouliere, Florent, El Messaoudi, Safia, Gongora, Celine, Guedj, Anne-Sophie, Robert, Bruno, Del Rio, Maguy, Molina, Franck, Lamy, Pierre-Jean, Lopez-Crapez, Evelyne, Mathonnet, Muriel, Ychou, Marc, Pezet, Denis, Thierry, Alain R
Médium: Artigo
Jazyk:Inglês
Vydáno: Neoplasia Press Inc. 2013
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3660801/
https://ncbi.nlm.nih.gov/pubmed/23730412
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