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OX40L/Jagged1 co-signaling by GM-CSF induced bone-marrow dendritic cells is required for the expansion of functional Tregs

Earlier, we had demonstrated that treatment with low dose of GM-CSF can prevent the development of experimental autoimmune thyroiditis (EAT), myasthenia gravis (EAMG) and type-1 diabetes; and could also reverse ongoing EAT and EAMG. The protective effect was mediated through the induction of tolerog...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gopisetty, Anupama, Bhattacharya, Palash, Haddad, Christine, Bruno, Joseph C., Vasu, Chenthamarakshan, Miele, Lucio, Prabhakar, Bellur S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3660466/
https://ncbi.nlm.nih.gov/pubmed/23630352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202298
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