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A 43-kDa TDP-43 Species Is Present in Aggregates Associated with Frontotemporal Lobar Degeneration

The transactive response DNA-binding protein (TDP-43) is a major component of the abnormal intracellular inclusions that occur in two common neurodegenerative diseases of humans: (1) a subtype of frontotemporal lobar degeneration and (2) amyotrophic lateral sclerosis. Genetics, experiments in cultur...

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Detalhes bibliográficos
Main Authors: Bosque, Patrick J., Boyer, Philip J., Mishra, Priya
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3660417/
https://ncbi.nlm.nih.gov/pubmed/23704877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062301
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