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Transcriptome Analysis of Genes Regulated by Cholesterol Loading in Two Strains of Mouse Macrophages Associates Lysosome Pathway and ER Stress Response with Atherosclerosis Susceptibility

Cholesterol loaded macrophages in the arterial intima are the earliest histological evidence of atherosclerosis. Studies of mouse models of atherosclerosis have shown that the strain background can have a significant effect on lesion development. We have previously shown that DBA/2 ApoE(−/−) mice ha...

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Bibliografski detalji
Glavni autori: Berisha, Stela Z., Hsu, Jeffrey, Robinet, Peggy, Smith, Jonathan D.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3660362/
https://ncbi.nlm.nih.gov/pubmed/23705026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065003
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