Stromal cell derived factor-1alpha protects stem cell derived insulin-producing cells from glucotoxicity under high glucose conditions in-vitro and ameliorates drug induced diabetes in rats

BACKGROUND: Diabetes mellitus is affecting more than 300 million people worldwide. Current treatment strategies cannot prevent secondary complications. Stem cells due to their regenerative power have long been the attractive target for the cell-based therapies. Mesenchymal stem cells (MSCs) possess...

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Auteurs principaux: Tariq, Muhammad, Masoud, Muhammad Sharif, Mehmood, Azra, Khan, Shaheen N, Riazuddin, Sheikh
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2013
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3660237/
https://ncbi.nlm.nih.gov/pubmed/23648189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-11-115
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