Involvement of TGFβ1 in autocrine regulation of proplatelet formation in healthy subjects and patients with primary myelofibrosis

Megakaryocytes release platelets into the bloodstream by elongating proplatelets. In this study, we showed that human megakaryocytes constitutively release Transforming Growth Factor β1 and express its receptors. Importantly, Transforming Growth Factor β1 downstream signaling, through SMAD2/3 phosph...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Badalucco, Stefania, Di Buduo, Christian Andrea, Campanelli, Rita, Pallotta, Isabella, Catarsi, Paolo, Rosti, Vittorio, Kaplan, David L., Barosi, Giovanni, Massa, Margherita, Balduini, Alessandra
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2013
Assuntos:
Original Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3659980/
https://ncbi.nlm.nih.gov/pubmed/23403314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2012.076752
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados