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Human FcγRII Cytoplasmic Domains Differentially Influence Antibody-Mediated Dengue Virus Infection

Ab-dependent enhancement (ADE) of dengue virus (DENV) infection is mediated through the interaction of viral immune complexes with FcγRs, with notable efficiency of FcγRII. Most human dengue target cells coexpress activating (FcγRIIa) and inhibitory (FcγRIIb) isoforms, but their relative roles in AD...

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Detalhes bibliográficos
Main Authors: Boonnak, Kobporn, Slike, Bonnie M., Donofrio, Gina C., Marovich, Mary A.
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3659957/
https://ncbi.nlm.nih.gov/pubmed/23616574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1203052
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