Efficient Lentiviral Transduction of Human Mesenchymal Stem Cells That Preserves Proliferation and Differentiation Capabilities

Long-term lentiviral transduction of human mesenchymal stem cells (hMSCs) greatly enhances the usefulness of these cells. However, such transduction currently requires the use of polybrene, which severely inhibits hMSC proliferation. In contrast, protamine sulfate at 100 μg/ml doubled transduction e...

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Bibliografski detalji
Glavni autori: Lin, Paul, Lin, Yuan, Lennon, Donald P., Correa, Diego, Schluchter, Mark, Caplan, Arnold I.
Format: Artigo
Jezik:Inglês
Izdano: AlphaMed Press 2012
Teme:
Enabling Technologies for Cell-Based Clinical Translation
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3659678/
https://ncbi.nlm.nih.gov/pubmed/23283550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2012-0086
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