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Emerging role of junctophilin-2 as a regulator of calcium handling in the heart

Junctophilin-2 (JPH2) is a membrane-binding protein that plays a key role in the organization of the junctional membrane complex (JMC) in cardiac myocytes. JPH2 is believed to keep the plasma membrane and sarcoplasmic reticulum at a fixed distance within the JMC, which is essential for proper Ca(2+)...

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Bibliographic Details
Main Authors: Garbino, Alejandro, Wehrens, Xander HT
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3659429/
https://ncbi.nlm.nih.gov/pubmed/20694023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2010.116
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