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The transcobalamin receptor knockout mouse: a model for vitamin B(12) deficiency in the central nervous system
The membrane receptor (TCblR/CD320) for transcobalamin (TC)-bound cobalamin (Cbl) facilitates the cellular uptake of Cbl. A genetically modified mouse model involving ablation of the CD320 gene was generated to study the effects on cobalamin homeostasis. The nonlethal nature of this knockout and the...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Federation of American Societies for Experimental Biology
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3659357/ https://ncbi.nlm.nih.gov/pubmed/23430977 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-219055 |
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