A copper sulfate and hydroxylysine treatment regimen for enhancing collagen cross-linking and biomechanical properties in engineered neocartilage

The objective of this study was to improve the biomechanical properties of engineered neotissues through promoting the development of collagen cross-links. It was hypothesized that supplementing medium with copper sulfate and the amino acid hydroxylysine would enhance the activity of lysyl oxidase e...

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Bibliographic Details
Main Authors: Makris, Eleftherios A., MacBarb, Regina F., Responte, Donald J., Hu, Jerry C., Athanasiou, Kyriacos A.
Format: Artigo
Language:Inglês
Published: Federation of American Societies for Experimental Biology 2013
Subjects:
Research Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3659348/
https://ncbi.nlm.nih.gov/pubmed/23457219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-224030
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