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Role of ABC transporters in lipid transport and human disease

Almost half of the 48 human ATP binding cassette (ABC) transporter proteins are thought to facilitate the ATP-dependent translocation of lipids or lipid-related compounds. Such substrates include cholesterol, plant sterols, bile acids, phospholipids and sphingolipids. Mutations in a substantial numb...

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Detalhes bibliográficos
Main Authors: Tarling, Elizabeth J., de Aguiar Vallim, Thomas Q., Edwards, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3659191/
https://ncbi.nlm.nih.gov/pubmed/23415156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tem.2013.01.006
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