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Modeling Autism by SHANK Gene Mutations in Mice

Shank family proteins (Shank1, Shank2, and Shank3) are synaptic scaffolding proteins that organize an extensive protein complex at the postsynaptic density (PSD) of excitatory glutamatergic synapses. Recent human genetic studies indicate that SHANK family genes (SHANK1, SHANK2, and SHANK3) are causa...

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Detalles Bibliográficos
Main Authors: Jiang, Yong-hui, Ehlers, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3659167/
https://ncbi.nlm.nih.gov/pubmed/23583105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2013.03.016
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