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Modeling Autism by SHANK Gene Mutations in Mice
Shank family proteins (Shank1, Shank2, and Shank3) are synaptic scaffolding proteins that organize an extensive protein complex at the postsynaptic density (PSD) of excitatory glutamatergic synapses. Recent human genetic studies indicate that SHANK family genes (SHANK1, SHANK2, and SHANK3) are causa...
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| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3659167/ https://ncbi.nlm.nih.gov/pubmed/23583105 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2013.03.016 |
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