Nuclear Aggregation of Olfactory Receptor Genes Governs Their Monogenic Expression

Gene positioning and regulation of nuclear architecture are thought to influence gene expression. Here, we show that, in mouse olfactory neurons, silent olfactory receptor (OR) genes from different chromosomes converge in a small number of heterochromatic foci. These foci are OR exclusive and form i...

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Detalhes bibliográficos
Main Authors: Clowney, E. Josephine, LeGros, Mark A., Mosley, Colleen P., Clowney, Fiona G., Markenskoff-Papadimitriou, Eirene C., Myllys, Markko, Barnea, Gilad, Larabell, Carolyn A., Lomvardas, Stavros
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3659163/
https://ncbi.nlm.nih.gov/pubmed/23141535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.09.043
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