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Monitoring and Manipulating Mammalian Unfolded Protein Response
The unfolded protein response (UPR) is a conserved, intracellular signaling pathway activated by endoplasmic reticulum (ER) stress. In mammalian cells, the UPR is controlled by three ER-resident transmembrane proteins: inositol-requiring enyzme-1 (IRE1), PKR-like ER kinase (PERK), and activating tra...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3658618/ https://ncbi.nlm.nih.gov/pubmed/21329801 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-385928-0.00011-0 |
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