Feasibility of proposed single-nucleotide polymorphisms as predictive markers for targeted regimens in metastatic colorectal cancer

BACKGROUND: Surrogate biomarkers for metastatic colorectal cancer (mCRC) are urgently needed to achieve the best outcomes for targeted therapy. METHODS: A clinical association analysis was performed to examine the three single-nucleotide polymorphisms (SNPs) that were previously proposed as markers...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kim, J C, Ha, Y J, Roh, S A, Choi, E Y, Yoon, Y S, Kim, K P, Hong, Y S, Kim, T W, Cho, D H, Kim, S Y, Kim, Y S
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2013
Schlagworte:
Molecular Diagnostics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3658526/
https://ncbi.nlm.nih.gov/pubmed/23579219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.163
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