CYP2A6 and ERCC1 polymorphisms correlate with efficacy of S-1 plus cisplatin in metastatic gastric cancer patients

BACKGROUND: We evaluated the association between polymorphisms of cytochrome P450 2A6 (CYP2A6)/excision repair cross-complementation group 1 (ERCC1)/X-ray repair cross-complementing group 1(XRCC1) and treatment outcomes of metastatic gastric cancer (MGC) patients treated with S-1/cisplatin. METHODS:...

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Detalhes bibliográficos
Main Authors: Park, S R, Kong, S-Y, Nam, B-H, Choi, I J, Kim, C G, Lee, J Y, Cho, S J, Kim, Y W, Ryu, K W, Lee, J H, Rhee, J, Park, Y-I, Kim, N K
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3068488/
https://ncbi.nlm.nih.gov/pubmed/21364592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2011.24
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