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A valid formulation of the analysis of noninferiority trials under random effects meta-analysis
A noninferiority (NI) trial is sometimes employed to show efficacy of a new treatment when it is unethical to randomize current patients to placebo because of the established efficacy of a standard treatment. Under this framework, if the NI trial determines that the treatment advantage of the standa...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3658490/ https://ncbi.nlm.nih.gov/pubmed/22467938 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biostatistics/kxs006 |
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