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A Single Mutant, A276S of p53 Turns the Switch to Apoptosis
The tumor suppressor protein p53 induces apoptosis, cell cycle arrest, and DNA repair along with other functions in a transcription-dependent manner(1). The selection of these functions depends on sequence-specific recognition of p53 to a target decameric sequence of gene promoters(2). Amino acid re...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3658472/ https://ncbi.nlm.nih.gov/pubmed/23402381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp300598k |
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