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A Single Mutant, A276S of p53 Turns the Switch to Apoptosis
The tumor suppressor protein p53 induces apoptosis, cell cycle arrest, and DNA repair along with other functions in a transcription-dependent manner(1). The selection of these functions depends on sequence-specific recognition of p53 to a target decameric sequence of gene promoters(2). Amino acid re...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3658472/ https://ncbi.nlm.nih.gov/pubmed/23402381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp300598k |
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