Llwytho...
Controlled Access of p53 to the Nucleus Regulates its Proteasomal Degradation by MDM2
The tumor suppressor p53 can be sent to the proteasome for degradation by placing its nucleo-cytoplasmic shuttling under ligand control. Endogenous p53 is ubiquitinated by MDM2 in the nucleus, and controlling the access of p53 to the nuclear compartment regulates its ubiquitination and proteasomal d...
Wedi'i Gadw mewn:
| Prif Awduron: | , , |
|---|---|
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2013
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3658471/ https://ncbi.nlm.nih.gov/pubmed/23398638 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp300543t |
| Tagiau: |
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