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The tumor microenvironment is a dominant force in multidrug resistance

The emergence of clinical drug resistance is still one of the most challenging factors in cancer treatment effectiveness. Until more recently, the assumption has been that random genetic lesions are sufficient to explain the progression of malignancy and escape from chemotherapy. Here we propose an...

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Autori principali: Correia, Ana Luísa, Bissell, Mina J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3658318/
https://ncbi.nlm.nih.gov/pubmed/22335920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drup.2012.01.006
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