Imaging tumor-stroma interactions during chemotherapy reveals contributions of the microenvironment to resistance

Little is known about the dynamics of cancer cell death in response to therapy in the tumor microenvironment. Intravital microscopy of chemotherapy-treated mouse mammary carcinomas allowed us to follow drug distribution, cell death and tumor-stroma interactions. We observed associations between vasc...

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Main Authors: Nakasone, Elizabeth S., Askautrud, Hanne A., Kees, Tim, Park, Jae-Hyun, Plaks, Vicki, Ewald, Andrew J., Fein, Miriam, Rasch, Morten G., Tan, Ying-Xim, Qiu, Jing, Park, Juwon, Sinha, Pranay, Bissell, Mina J., Frengen, Eirik, Werb, Zena, Egeblad, Mikala
Format: Artigo
Jezik:Inglês
Izdano: 2012
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3332002/
https://ncbi.nlm.nih.gov/pubmed/22516258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2012.02.017
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