Imaging tumor-stroma interactions during chemotherapy reveals contributions of the microenvironment to resistance

Little is known about the dynamics of cancer cell death in response to therapy in the tumor microenvironment. Intravital microscopy of chemotherapy-treated mouse mammary carcinomas allowed us to follow drug distribution, cell death and tumor-stroma interactions. We observed associations between vasc...

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Hlavní autoři: Nakasone, Elizabeth S., Askautrud, Hanne A., Kees, Tim, Park, Jae-Hyun, Plaks, Vicki, Ewald, Andrew J., Fein, Miriam, Rasch, Morten G., Tan, Ying-Xim, Qiu, Jing, Park, Juwon, Sinha, Pranay, Bissell, Mina J., Frengen, Eirik, Werb, Zena, Egeblad, Mikala
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3332002/
https://ncbi.nlm.nih.gov/pubmed/22516258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2012.02.017
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