Extracellular ATP mediates mast cell-dependent intestinal inflammation through P2X7 purinoceptors

Mast cells are known effector cells in allergic and inflammatory diseases, but their precise roles in intestinal inflammation remain unknown. Here we show that activation of mast cells in intestinal inflammation is mediated by ATP-reactive P2X7 purinoceptors. We find an increase in the numbers of ma...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Kurashima, Yosuke, Amiya, Takeaki, Nochi, Tomonori, Fujisawa, Kumiko, Haraguchi, Takeshi, Iba, Hideo, Tsutsui, Hiroko, Sato, Shintaro, Nakajima, Sachiko, Iijima, Hideki, Kubo, Masato, Kunisawa, Jun, Kiyono, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2012
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3658010/
https://ncbi.nlm.nih.gov/pubmed/22948816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2023
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados