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Small Molecule Tyrosine Kinase Inhibitors for the Treatment of Intestinal Inflammation

BACKGROUND: We developed a series of dendritic cell autoimmune modulators (DCAMs) based on small molecule Flt3 receptor tyrosine kinase inhibitors (TKIs) for the inhibition of intestinal inflammation and oral delivery. METHODS: DCAMs were administered orally during and after induction of dextran sod...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sidhu, Maninder, Cotoner, Carmen Alonso, Guleng, Bayasi, Arihiro, Seiji, Chang, Sunyoung, Duncan, Kenneth W., Ajami, Alfred M., Chau, MyDoanh, Reinecker, Hans-Christian
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3657752/
https://ncbi.nlm.nih.gov/pubmed/21438094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ibd.21646
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