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Mislocalization of neuronal mitochondria reveals regulation of Wallerian degeneration and NMNAT/WLD(S)-mediated axon protection independent of axonal mitochondria

Axon degeneration is a common and often early feature of neurodegeneration that correlates with the clinical manifestations and progression of neurological disease. Nicotinamide mononucleotide adenylytransferase (NMNAT) is a neuroprotective factor that delays axon degeneration following injury and i...

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Detalhes bibliográficos
Main Authors: Kitay, Brandon M., McCormack, Ryan, Wang, Yunfang, Tsoulfas, Pantelis, Zhai, R. Grace
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3657477/
https://ncbi.nlm.nih.gov/pubmed/23314018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt009
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