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Wld(S) requires Nmnat1 enzymatic activity and N16–VCP interactions to suppress Wallerian degeneration

Slow Wallerian degeneration (Wld(S)) encodes a chimeric Ube4b/nicotinamide mononucleotide adenylyl transferase 1 (Nmnat1) fusion protein that potently suppresses Wallerian degeneration, but the mechanistic action of Wld(S) remains controversial. In this study, we characterize Wld(S)-mediated axon pr...

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Detalhes bibliográficos
Main Authors: Avery, Michelle A., Sheehan, Amy E., Kerr, Kimberly S., Wang, Jing, Freeman, Marc R.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654119/
https://ncbi.nlm.nih.gov/pubmed/19237597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200808042
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