Prevalence of K-RAS Codons 12 and 13 Mutations in Locally Advanced Head and Neck Squamous Cell Carcinoma and Impact on Clinical Outcomes

Background. RAS gene mutations have an impact on treatment response and overall prognosis for certain types of cancer. Objectives. To determine the prevalence and impact of K-RAS codons 12 and 13 mutations in patients with locally advanced HNSCC treated with primary or adjuvant chemo-radiation. Meth...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Bissada, Eric, Abboud, Olivier, Abou Chacra, Zahi, Guertin, Louis, Weng, Xiaoduan, Nguyen-Tan, Phuc Félix, Tabet, Jean-Claude, Thibaudeau, Ève, Lambert, Louise, Audet, Marie-Lise, Fortin, Bernard, Soulières, Denis
Format: Artigo
Langue:Inglês
Publié: Hindawi Publishing Corporation 2013
Sujets:
Clinical Study
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3657450/
https://ncbi.nlm.nih.gov/pubmed/23737793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/848021
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