Dual Inhibition of Autophagy and PI3K/AKT/MTOR Pathway as a Therapeutic Strategy in Head and Neck Squamous Cell Carcinoma

Genomic analyses of head and neck squamous cell carcinoma (HNSCC) have highlighted alterations in the phosphatidylinositol 3-kinase (PI3K) signaling pathway, presenting a therapeutic target for multiple ongoing clinical trials with PI3K or PI3K/MTOR inhibitors. However, these inhibitors can potentia...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Bernard, Monique, Cardin, Guillaume B., Cahuzac, Maxime, Ayad, Tareck, Bissada, Eric, Guertin, Louis, Bahig, Houda, Nguyen-Tan, Phuc Felix, Filion, Edith, Ballivy, Olivier, Soulieres, Denis, Rodier, Francis, Christopoulos, Apostolos
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7563873/
https://ncbi.nlm.nih.gov/pubmed/32825725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12092371
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