Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers

A large number of tiny noncoding RNAs have been cloned and named microRNAs (miRs). Recently, we have reported that miR-15a and miR-16a, located at 13q14, are frequently deleted and/or down-regulated in patients with B cell chronic lymphocytic leukemia, a disorder characterized by increased survival....

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Bibliographic Details
Main Authors: Calin, George Adrian, Sevignani, Cinzia, Dumitru, Calin Dan, Hyslop, Terry, Noch, Evan, Yendamuri, Sai, Shimizu, Masayoshi, Rattan, Sashi, Bullrich, Florencia, Negrini, Massimo, Croce, Carlo M.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2004
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC365734/
https://ncbi.nlm.nih.gov/pubmed/14973191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0307323101
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