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The role of the cilium in normal and abnormal cell cycles: emphasis on renal cystic pathologies
The primary cilium protrudes from the cell surface and acts as a sensor for chemical and mechanical growth cues, with receptors for a number of growth factors (PDGFα, Hedgehog, Wnt, Notch) concentrated within the ciliary membrane. In normal tissues, the cilium assembles after cells exit mitosis and...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3657316/ https://ncbi.nlm.nih.gov/pubmed/22782110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-012-1052-z |
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