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The role of the cilium in normal and abnormal cell cycles: emphasis on renal cystic pathologies
The primary cilium protrudes from the cell surface and acts as a sensor for chemical and mechanical growth cues, with receptors for a number of growth factors (PDGFα, Hedgehog, Wnt, Notch) concentrated within the ciliary membrane. In normal tissues, the cilium assembles after cells exit mitosis and...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3657316/ https://ncbi.nlm.nih.gov/pubmed/22782110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-012-1052-z |
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