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Ghrelin cells replace insulin-producing β cells in two mouse models of pancreas development
The pancreatic islet is necessary for maintaining glucose homeostasis. Within the pancreatic islet, the homeodomain protein Nkx2.2 is essential for the differentiation of all insulin-producing β cells and a subset of glucagon-producing α cells (1). Mice lacking Nkx2.2 have relatively normal sized is...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC365721/ https://ncbi.nlm.nih.gov/pubmed/14970313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308604100 |
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